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  • Is Mindfulness The Answer?

    by Susan December 10, 2010 at 3:16 am

    Depression is easy enough to treat with anti-depressant medication and counselling in some cases but the problem tends to lie in the conditions perseverance in recurring. The answer to how to keep depression at bay permanently once it has been treated successfully is as yet undiscovered but some recent findings from The Center for Addiction and Mental Health in Toronto show that it may not be too far away.

    Zindel Segal, who is based at the center, carried out a study comparing mindfulness based therapy and maintenance anti-depressant therapy with some interesting results. 166 random patients between the ages of 18 and 65 who suffered from major depressive disorders, were invited to testing at two outpatient centres in Canada. Three groups were created – one who were treated with mindfulness based cognitive therapy, one with antidepressant maintenance therapy and third with a placebo. The patients who received cognitive therapy continued with their normal use of antidepressants and attended eight weekly group sessions.

    The treatment effects on the 51% of patients who were assessed as unstable remitters at the end of the study were examined. The findings stated that the two groups who received treatment had a reduced risk of relapse whereas the placebo group had no change. Relapse rates were 28% for mindfulness cognitive therapy, 27% for antidepressant maintenance therapy and 71% for the group who received a placebo.  ”For patients whose acute-phase remission was marked by periodic symptom flurries, discontinuing antidepressants and receiving cognitive therapy, or continuing with antidepressants significantly lowered relapse/recurrence risk compared with discontinuation to placebo” was stated in the report.

    This findings are in line with findings in previous studies regarding remission however, it was decided that further study is needed before a conclusive result can be found.




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    Probiotic Benefits For Children

    by Susan November 30, 2010 at 3:06 am

    Although it is the subject of some debate, a leading medical group in Chicago have found evidence that probiotics do indeed have benefits for children. The effects are limited and it only applies to certain illnesses, but the findings are interesting nonetheless.

    The findings are not conclusive enough as yet to advocate the addition of probiotics in infant formula and they definitely should not be administered to children with serious illnesses. This information is included in a report published recently in Pediatrics journal by the American Academy of Pediatrics.

    Companies have long claimed that natural bacteria found in the intestinal tract can be enhanced by probiotic pills and dairy products, resulting in a healthier immune and digestive system. The new report covers a summary of the findings found in the recent tests, which suggest that probiotics may help children suffering from minor complaints such as diarrhoea caused by a virus or by taking antibiotics.

    This claim may well be further substantiated by future research but one warning is clear: children who are receiving intravenous medication or who have compromised immune systems should not use probiotics due to the increased risk of infection.




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    New Low-Cost Vaccination Method

    by Susan November 17, 2010 at 2:56 am

    Rotavirus, a severe diarrhoeal disease which is responsible for approximately half a million child deaths a year, may soon be a lot easier to control due to a new discovery. A team from the Cummings School of Veterinary Medicine at Tufts University and Tufts University School of Medicine worked with their counterparts from Boston and Tulane Universities on a study which has had amazing results.

    The study, published in this month’s issue of Clinical and Vaccine Immunology, shows a vaccine which is delivered nasally and has been proven to combat the spread of rotavirus in mice. Testing has shown that this new method can safely be used for tetanus and is currently being tested with other immunisations such as diphteria. Without the need for refrigeration that current vaccines have, this new method would greatly reduce the cost involved in immunising people in developing countries. Availability in the form of nasal drops makes it more easily transportable and negates the need for a sterile environment. It also makes the lack of trained personnel less of a problem.

    “In addition to being heat-stable and low-cost, the B. subtilis vaccines are given in the form of nasal drops or spray. A needle-free approach to vaccination is particularly advantageous in developing countries where clean needles and syringes and trained personnel are not always available,” said team leader Abraham L. (Linc) Sonenshein, PhD, professor and acting chair of molecular biology and microbiology at TUSM.

    “This vaccine project is still in the developmental stage,” he continued. “The next major step for these vaccines is to show that they are safe and work well in humans, and then to extend the rotavirus and tetanus vaccine technology to include diphtheria, pertussis and other infectious diseases. Those diseases cause tens of thousands of deaths, particularly in newborns and in South-East Asia. We are actively looking for partners in the US and around the world to help us pursue our goal of reaching the point where many childhood and adult vaccines can be manufactured in a way that avoids the need for injection or refrigeration. Jerry Keusch of Boston University School of Public Health and I started this project 15 years ago and it has taken a long time to reach the stage where we now have effective needle-free vaccines. The technology has now advanced enough that we can expect to be successful with many other vaccines in a short time frame.”




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